3-fpm crystalline ( 3-Fluorophenmetrazine ) (also known as 3-FPM, 3-FPH and PAL-593) is a phenylmorpholine-based stimulant and fluorinated analogue of phenmetrazine that has been sold online as a designer drug.
Stereoisomers
3-FPM is a derivative of phenmetrazine. As described by McLaughlin and colleagues
(7), the fluorinated analogs of phenmetrazine contain two chiral centers which yield the potential for four stereoisomers and two racemic mixtures (i.e., cis- and trans-racemates) (See Fig. 1 in McLaughlin et al).
Physical appearance of 3-fpm crystalline
3-Fluorophenmetrazine is a white, solid, crystalline powder. It was also identified in
yellow, blue or green pellets (tablets).
Chemical name
IUPAC name: 2-(3-fluorophenyl)–3-methylmorpholine; hydrochloride.
Identification and analysis
A number of analytical tests have been used to differentiate 3-FPM from its positional isomers, 2- and 4-FPM, including gas chromatography-mass spectrometry, liquid chromatography-mass spectrometry, and thin-layer chromatography (7). All of the methods successfully differentiated 3-FPM from its.
Pharmacodynamics
3-FPM is potent at releasing dopamine (DA) and norepinephrine (NE), with half
maximal effective concentration (EC50) values of 43 and 30 nM, respectively, and
less potent at releasing serotonin (5-HT; 2558 nM (1)).
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